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26 نوفمبر 2013
Postdoc position noncoding RNAs in Developmental Neuroscience
Job Description
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A FUNDEDPOSTDOCTORALPOSITION is available within the G. ArmeniseHarvard laboratory of Axonal biology Center for Integrative Biology CIBIO University of Trento.
Background Brain wiring occurs during the development of the nervous system and ensures the formation ofplex networks of intermunicating neurons. This process is considered essential during development because these circuits once they are formed constitute the basis of any brain activity from basic processing of sensory information to higher cognitive functions. Miswriring can have devastating consequences. To avoid any routing errors of axons through which neurons are connected vast andplex arrays of regulatory mechanisms are in place during development. Elucidating these mechanisms is the object of intense research in the field. In particular noncoding RNAs including microRNAs newly shown to be key regulatory molecules in virtually all eukaryotic cells from plant to human have been suspected to play important roles in the establishment of neuronal networks. But their mode of functions in this process are still largely unknown.
Project Title noncoding RNAs Roles and Mode of Action in Brain Wiring
Scope of the projectacirc128uml This project aims to uncover the noncoding RNAs that are key in the early stages of neuronal network formation namely axon outgrowth and guidance and to decipher their modes of action. A wide array of wellestablished but also cuttingage techniques will be used for the aplishment of this project such as Next Generation Sequencing live imaging and chemotropic assays.
Locationacirc128uml The project is to be conducted within CIBIO at the University of Trento located in the heart of the Alps. CIBIO is a new international and multidisciplinary research center equipped with stateoftheart technologies.
Laboratory The host laboratory is headed by MarieLaure Baudet and is funded by several grant including a 1 million dollar grant awarded by the G. ArmeniseHarvard foundation. It has ongoing collaborations with the University of Cambridge UK EMBL Heidelberg Germany and LANGEBIO Mexico. More information can be found on
1 ML Baudet publication track record
www.ncbi.nlm.nih.govpubmed?termbaudetML5BAU5D
2 Key funding body
www.armeniseharvard.orgitalycda
3 Host laboratory
www.unitn.itencibio23651thegiovanniarmeniseharvardlaboratoryofaxonalneurobiologyCandidate profileacirc128uml Candidates with strong background in RNA Molecular Biology and holding a PhD degree are encouraged to apply. Prior experience with lasercapture microdissection would be desirable. The successful candidate should be highly motivated display initiative and independence and have excellent verbal and written Englishmunication skills.
Interested candidates should send a CV toacirc128uml
via http://qatar.tanqeeb.com/jobs-in-qatar/it/003418353.html
